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Medically assisted hydration for palliative care patients [Новость добавлена - 07.05.2008]

P Good, J Cavenagh, M Mather, P Ravenscroft Cochrane Database of Systematic Reviews 2008 Issue 2 (Status: New)Copyright © 2008 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.


DOI: 10.1002/14651858.CD006273.pub2   This version first published online: 16 April 2008 in Issue 2, 2008

This record should be cited as: Good P, Cavenagh J, Mather M, Ravenscroft P. Medically assisted hydration for palliative care patients. Cochrane Database of Systematic Reviews 2008, Issue 2. Art. No.: CD006273. DOI: 10.1002/14651858.CD006273.pub2.
Abstract

Background
Many palliative care patients have reduced oral intake during their illness. The management of this can include the provision of medically assisted hydration with the aim of prolonging the length of life of a patient, improving their quality of life, or both.

Objectives
To determine the effect of medically assisted hydration in palliative care patients on their quality and length of life.

Search strategy
Studies were identified from searching CENTRAL, MEDLINE (1966 to 2008), EMBASE (1980 to 2008), CINAHL, CANCERLIT, Caresearch, Dissertation abstracts, SCIENCE CITATION INDEX and the reference lists of all eligible studies, key textbooks, and previous systematic reviews. The date of the latest search was February 2008.

Selection criteria
All relevant randomised controlled trials (RCTs) or prospective controlled studies of medically assisted hydration in palliative care patients.

Data collection and analysis
Five relevant studies were identified. These included two RCTs (93 participants), and three prospective controlled trials (360 participants). These were assessed independently by two review authors for quality and validity. The small number of studies and the heterogeneity of the data meant that a quantitative analysis was not possible, so a description of the main findings was included only.

Main results
One study found that sedation and myoclonus (involuntary contractions of muscles) were improved more in the intervention group (28 - hydration, 23 - placebo). Another study found that dehydration was significantly higher in the non-hydration group, but that some fluid retention symptoms (pleural effusion, peripheral oedema and ascites) were significantly higher in the hydration group (59 - hydration group, 167 - non -hydration group). The other three studies did not show significant differences in outcomes between the two groups.

Authors' conclusions
There are insufficient good quality studies to make any recommendations for practice with regard to the use of medically assisted hydration in palliative care patients.

Plain language summary
Medically assisted hydration to assist palliative care patients

It is common for palliative care patients to have reduced fluid intake during their illness. Management of this condition includes discussion with the patient, family and staff involved and may include the provision of fluids with medical assistance. This can be performed using a small plastic tube inserted into a vein or subcutaneous tissue, or via a tube inserted into the stomach. It is unknown whether this treatment helps people to feel better or live longer. A search of the international literature was only able to find a small number of studies looking at this issue. As a result, it is not possible to clearly define the benefits and harms of this treatment.

http://www.mrw.interscience.wiley.com/cochrane/clsysrev/articles/CD006273/frame.html